50 days of prayer is conducted in the centre by Fr.Reni Pullukalayil. Only 30 seats are available. One week retreat and three days of Thapas are included in this 50 days. The sisters are given opportunity for personal prayer as well as community prayers. According to the need of the sisters there will be spiritual sharing and guidance. 50 Days prayer retreat mainly focus at infilling of the Holy Spirit and deepening of the Love of God.